Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | PREP | P48147 | 3/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.53 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14999594 | 1.00 | FKBP1A (0.55) | FKBP1AHTR2CPREPTMEM97SIGMAR1 | |
| SCHEMBL25756732 | 0.99 | FKBP1A (0.56) | FKBP1AHTR2CPREPTMEM97SIGMAR1 | |
| SCHEMBL14646671 | 0.99 | FKBP1A (0.56) | FKBP1AHTR2CPREPTMEM97SIGMAR1 | |
| SCHEMBL1355641 | 0.94 | PREP (0.59) | HTR2CPREPACE2PDK1PDK2 | |
| SCHEMBL15372095 | 0.94 | PREP (0.59) | HTR2CPREPACE2PDK1PDK2 | |
| SCHEMBL1355639 | 0.94 | PREP (0.59) | HTR2CPREPACE2PDK1PDK2 | |
| SCHEMBL28411733 | 0.89 | HTR2C (0.59) | HTR2CPREPPDK1PDK2PDK3 | |
| SCHEMBL25841627 | 0.89 | HTR2C (0.59) | HTR2CPREPPDK1PDK2PDK3 | |
| SCHEMBL16925462 | 0.85 | PREP (0.56) | HTR2CPREPACE2PDK1PDK2 | |
| SCHEMBL7648946 | 0.84 | PREP (0.61) | FKBP1APREPALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114980976-A | Covalent RAS inhibitors and uses thereof | 锐新医药公司 | 2022-08-30 | — | — | CN | disclosed |