Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acerogenin E SCHEMBL23268432 | 1.00 | NFKB1 (0.45) | NFKB1NFKB2RELATRIM24TRIM33 | |
| SCHEMBL15112755 | 0.79 | NFKB1 (0.42) | NFKB1NFKB2RELA | |
| Myricanone SCHEMBL29904784 | 0.78 | NFKB1 (0.60) | NFKB1NFKB2RELAALDH1A1ESR2 | |
| Myricanone SCHEMBL432252 | 0.78 | NFKB1 (0.60) | NFKB1NFKB2RELAALDH1A1ESR2 | |
| Acerogenin C SCHEMBL4112475 | 0.76 | NFKB1 (0.56) | NFKB1NFKB2RELANR1H2NR1H3 | |
| SCHEMBL21693012 | 0.74 | NFKB1 (0.53) | NFKB1NFKB2RELAKDM4EMEN1 | |
| SCHEMBL21693008 | 0.72 | NFKB1 (0.48) | NFKB1NFKB2RELACNR2KDM4E | |
| Acerogenin K SCHEMBL13698051 | 0.71 | NFKB1 (0.47) | NFKB1NFKB2RELAALDH1A1CNR1 | |
| SCHEMBL16417520 | 0.70 | POLB (0.33) | NFKB1NFKB2RELAALDH1A1CNR1 | |
| SCHEMBL29900144 | 0.68 | CNR2 (0.38) | ALDH1A1CNR1CNR2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4267103-A1 | PLANT EXTRACTS FOR IMPROVING SKIN BARRIER FUNCTION | Oriflame Cosmetics AG (CH) | 2023-11-01 | — | — | EP | claimed |
| WO-2022135827-A1 | PLANT EXTRACTS FOR IMPROVING SKIN BARRIER FUNCTION | ORIFLAME COSMETICS AG (CH) | 2022-06-30 | — | — | WO | claimed |
| EP-4267103-A1 | PLANT EXTRACTS FOR IMPROVING SKIN BARRIER FUNCTION | Oriflame Cosmetics AG (CH) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022135827-A1 | PLANT EXTRACTS FOR IMPROVING SKIN BARRIER FUNCTION | ORIFLAME COSMETICS AG (CH) | 2022-06-30 | — | — | WO | disclosed |