Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22555052 | 1.00 | GPR119 (0.40) | GPR119KDM4EPKMKLK7STS | |
| SCHEMBL29889647 | 0.92 | GPR119 (0.40) | GPR119KDM4EPKMKLK7STS | |
| SCHEMBL6052905 | 0.90 | KLK7 (0.38) | GPR119KDM4EPKMKLK7STS | |
| SCHEMBL27043967 | 0.90 | KLK7 (0.38) | GPR119KDM4EPKMKLK7STS | |
| SCHEMBL6052900 | 0.90 | KLK7 (0.38) | GPR119KDM4EPKMKLK7STS | |
| SCHEMBL4378972 | 0.90 | KLK7 (0.38) | GPR119KDM4EPKMKLK7STS | |
| SCHEMBL30064881 | 0.90 | KLK7 (0.38) | GPR119KDM4EPKMKLK7STS | |
| SCHEMBL30977295 | 0.89 | GPR119 (0.38) | GPR119KDM4EPKMKLK7STS | |
| SCHEMBL23043370 | 0.88 | RIPK1 (0.37) | GPR119MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL26694476 | 0.88 | RIPK1 (0.37) | GPR119MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4322945-A2 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| WO-2022221528-A2 | KRAS G12C INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-10-20 | — | — | WO | disclosed |