Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22505554 | 1.00 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2GAAHPGDMAPT | |
| SCHEMBL24735596 | 0.91 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2GAAHPGDMAPT | |
| SCHEMBL24735338 | 0.91 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2GAAHPGDMAPT | |
| SCHEMBL24735235 | 0.91 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2GAAHPGDMAPT | |
| SCHEMBL24735181 | 0.84 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2GAAHPGDMAPT | |
| SCHEMBL6668947 | 0.84 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2GAAHPGDMAPT | |
| Hydrochloric Acid SCHEMBL1836445 | 0.83 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GAAHPGDHTT | |
| SCHEMBL20231855 | 0.82 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2GAAHPGDMAPT | |
| SCHEMBL29482949 | 0.82 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2GAAHPGDMAPT | |
| SCHEMBL26511741 | 0.82 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2GAAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115003295-B | Novel chroman derivatives having estrogen receptor degrading activity and uses thereof | 冰洲石生物科技公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-117229286-A | Aromatic compound, preparation method thereof and application thereof in preparation of estrogen receptor degradation agent | 海创药业股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-115003295-A | Novel chroman derivatives having estrogen receptor degrading activity and uses thereof | 冰洲石生物科技公司 | 2022-09-02 | — | — | CN | disclosed |