Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1836445 | 0.98 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1GAAADRA1BHPGD | |
| SCHEMBL29482949 | 0.84 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1GAAHPGDHTT | |
| SCHEMBL26511741 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1GAAHPGDACACB | |
| SCHEMBL20231855 | 0.84 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1GAAHPGDHTT | |
| SCHEMBL22505554 | 0.84 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1GAAHPGDHTT | |
| SCHEMBL29889809 | 0.84 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1GAAHPGDHTT | |
| SCHEMBL10277983 | 0.84 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1GAADPP4DPP9 | |
| SCHEMBL31289220 | 0.82 | CHRM4 (0.45) | SMN1; SMN2ALDH1A1ADRA1BADRA1DADRA1A | |
| SCHEMBL3551275 | 0.82 | MAPT (0.37) | SMN1; SMN2ALDH1A1GAAHPGDDPP4 | |
| SCHEMBL18003215 | 0.81 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1GAAADRA1BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020439-A2 | IMPROVED PROCESS FOR PREPARATION OF RISPERIDONE | NADKARNI SUNIL SADANAND (IN) | 2004-03-11 | — | — | WO | disclosed |
| US-6455531-B1 | METALLOPROTEINASE INHIBITORS | DARWIN DISCOVERY, LTD. (GB) | 2002-09-24 | — | — | US | disclosed |
| EP-1237868-A1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE (MMP) INHIBITORS | Darwin Discovery Limited (GB) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001044189-A1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE (MMP) INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-06-21 | — | — | WO | disclosed |