Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23514272 | 1.00 | PGR (0.59) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL19625923 | 1.00 | PGR (0.59) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL23514172 | 1.00 | PGR (0.59) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL21367331 | 0.95 | PGR (0.62) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL19625856 | 0.95 | PGR (0.62) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL23638353 | 0.95 | PGR (0.62) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL23223025 | 0.95 | PGR (0.62) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL29891105 | 0.88 | PGR (0.64) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL28600593 | 0.88 | PGR (0.61) | PGRCYP3A4ALDH1A1CYP2C19AR | |
| SCHEMBL29890662 | 0.88 | PGR (0.61) | PGRCYP3A4ALDH1A1CYP2C19AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109415404-B | Process and intermediates for 6, 7-alpha-epoxidation of steroid 4, 6-dienes | NZP英国有限公司 | 2022-08-26 | — | — | CN | disclosed |