Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17791449 | 0.83 | MAOA (0.44) | HRH3GBA1SLC6A4PARP1CHRM2 | |
| SCHEMBL12735989 | 0.82 | TAAR1 (0.47) | TAAR1HRH3EP300GBA1SLC6A4 | |
| SCHEMBL29890848 | 0.82 | EED (0.52) | TAAR1HRH3EP300GBA1SLC6A4 | |
| SCHEMBL26187550 | 0.82 | EED (0.52) | TAAR1HRH3EP300GBA1SLC6A4 | |
| SCHEMBL29889395 | 0.82 | EED (0.52) | TAAR1HRH3EP300GBA1SLC6A4 | |
| Hydrochloric Acid SCHEMBL30648851 | 0.81 | EED (0.51) | TAAR1HRH3EP300GBA1SLC6A4 | |
| SCHEMBL19524560 | 0.75 | TAAR1 (0.46) | TAAR1 | |
| Hydrochloric Acid SCHEMBL2634704 | 0.74 | GBA1 (0.61) | TAAR1EP300GBA1SLC6A4EED | |
| SCHEMBL15130164 | 0.74 | HRH3 (0.48) | HRH3GBA1SLC6A4PARP1CHRM2 | |
| SCHEMBL11636313 | 0.74 | SLC6A4 (0.45) | HRH3GBA1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056075-A2 | SIX MEMBERED HETEROAROMATIC INHIBITORS TARGETING RESISTANT KINASE MUTATIONS | TARGEGEN, INC. (US) | 2007-05-18 | — | — | WO | disclosed |