Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23410172 | 1.00 | ALDH1A1 (0.41) | ALDH1A1JAK2BTKKCNJ5KCNJ3 | |
| SCHEMBL23410196 | 0.85 | PSMB8 (0.43) | ALDH1A1KCNJ5KCNJ3KCNQ1CACNA1C | |
| SCHEMBL29891599 | 0.85 | PSMB8 (0.43) | ALDH1A1KCNJ5KCNJ3KCNQ1CACNA1C | |
| SCHEMBL23410174 | 0.83 | ALDH1A1 (0.37) | ALDH1A1JAK2BTKKCNJ5KCNJ3 | |
| SCHEMBL23410244 | 0.83 | JAK2 (0.42) | ALDH1A1JAK2BTKKDM4EEGFR | |
| SCHEMBL569008 | 0.76 | EGFR (0.55) | ALDH1A1KDM4EEGFRSRCKMT2A | |
| SCHEMBL29891965 | 0.76 | EGFR (0.55) | ALDH1A1KDM4EEGFRSRCKMT2A | |
| SCHEMBL25349889 | 0.74 | BCL6 (0.42) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL23410154 | 0.71 | KCNJ5 (0.48) | ALDH1A1KCNJ5KCNJ3KCNQ1CACNA1C | |
| SCHEMBL23410236 | 0.71 | KDM4E (0.42) | ALDH1A1KCNJ5KCNJ3KCNQ1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119564686-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119523983-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119424429-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-115003665-B | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-115003665-A | Substituted aminoquinolones as immunoactive DGK alpha inhibitors | 拜耳公司 | 2022-09-02 | — | — | CN | disclosed |