Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 9/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21657878 | 1.00 | NR1H2 (0.39) | NR1H2LMNAPOLBHSP90AA1HSP90AB1 | |
| SCHEMBL22829314 | 0.88 | HSP90AA1 (0.34) | NR1H2HSP90AA1HSP90AB1TTKBRD4 | |
| SCHEMBL29891149 | 0.88 | HSP90AA1 (0.34) | NR1H2HSP90AA1HSP90AB1TTKBRD4 | |
| SCHEMBL22829332 | 0.88 | HSP90AA1 (0.34) | NR1H2LMNAHSP90AA1HSP90AB1TTK | |
| SCHEMBL29890676 | 0.88 | GPR119 (0.36) | NR1H2HSP90AA1HSP90AB1TTKGPR119 | |
| SCHEMBL22829310 | 0.88 | GPR119 (0.36) | NR1H2HSP90AA1HSP90AB1TTKGPR119 | |
| SCHEMBL22838260 | 0.88 | HSP90AA1 (0.34) | NR1H2POLBHSP90AA1HSP90AB1TTK | |
| SCHEMBL22829313 | 0.88 | HSP90AA1 (0.34) | NR1H2HSP90AA1HSP90AB1TTKBRD4 | |
| SCHEMBL29890743 | 0.88 | HSP90AA1 (0.34) | NR1H2LMNAHSP90AA1HSP90AB1TTK | |
| SCHEMBL29891209 | 0.88 | HSP90AA1 (0.34) | NR1H2HSP90AA1HSP90AB1TTKBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110248940-B | Aryl hydrocarbon receptor (AhR) modulator compounds | 菲尼克斯药品股份公司 | 2022-07-01 | — | — | CN | disclosed |