Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29891149 | 1.00 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1GPR119NR1H2CNR1 | |
| SCHEMBL22829310 | 0.91 | GPR119 (0.36) | HSP90AA1HSP90AB1GPR119NR1H2CCR9 | |
| SCHEMBL29890676 | 0.91 | GPR119 (0.36) | HSP90AA1HSP90AB1GPR119NR1H2CCR9 | |
| SCHEMBL22829332 | 0.91 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1GPR119NR1H2HSD11B1 | |
| SCHEMBL29890743 | 0.91 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1GPR119NR1H2HSD11B1 | |
| SCHEMBL22838260 | 0.91 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1GPR119NR1H2CNR1 | |
| SCHEMBL21657878 | 0.88 | NR1H2 (0.39) | HSP90AA1HSP90AB1GPR119NR1H2HSD11B1 | |
| SCHEMBL29891744 | 0.88 | NR1H2 (0.39) | HSP90AA1HSP90AB1GPR119NR1H2HSD11B1 | |
| SCHEMBL22829300 | 0.88 | CCR9 (0.37) | HSP90AA1HSP90AB1GPR119NR1H2CCR9 | |
| SCHEMBL29890557 | 0.88 | CCR9 (0.37) | HSP90AA1HSP90AB1GPR119NR1H2CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110248940-B | Aryl hydrocarbon receptor (AhR) modulator compounds | 菲尼克斯药品股份公司 | 2022-07-01 | — | — | CN | disclosed |
| US-10981908-B2 | Aryl hydrocarbon receptor (AHR) modulator compounds | PHENEX PHARMACEUTICALS AG (DE) | 2021-04-20 | — | — | US | disclosed |
| US-10981908-B2 | Aryl hydrocarbon receptor (AHR) modulator compounds | PHENEX PHARMACEUTICALS AG (DE) | 2021-04-20 | — | — | US | disclosed |
| EP-3577112-B1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2020-12-30 | — | — | EP | disclosed |
| EP-3577112-B1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2020-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981908-B2 | Aryl hydrocarbon receptor (AHR) modulator compounds | AHR, ARNT, NR1H2 | HSP90AA1 1120/4885HSP90AB1 944/4885GPR119 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.