Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23410946 | 1.00 | KDM4E (0.40) | KDM4EMEN1KMT2AUSP2UPP1 | |
| SCHEMBL23411129 | 0.83 | MAOA (0.39) | KDM4EMEN1KMT2AUSP2MAPT | |
| SCHEMBL29892642 | 0.83 | MAOA (0.39) | KDM4EMEN1KMT2AUSP2MAPT | |
| SCHEMBL23411148 | 0.82 | KDM4E (0.36) | KDM4EMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL23410062 | 0.79 | EGLN1 (0.53) | KDM4EMEN1KMT2AMAPTLMNA | |
| SCHEMBL29891577 | 0.79 | EGLN1 (0.53) | KDM4EMEN1KMT2AMAPTLMNA | |
| SCHEMBL23410095 | 0.79 | GSK3B (0.45) | KDM4EMEN1KMT2AGAANPSR1 | |
| SCHEMBL29891687 | 0.77 | LMNA (0.41) | KDM4EMEN1KMT2AMAPTLMNA | |
| SCHEMBL23410160 | 0.77 | LMNA (0.41) | KDM4EMEN1KMT2AMAPTLMNA | |
| SCHEMBL23410902 | 0.77 | MAPT (0.41) | KDM4EMEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119564686-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119523983-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119424429-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-115003665-B | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-115003665-A | Substituted aminoquinolones as immunoactive DGK alpha inhibitors | 拜耳公司 | 2022-09-02 | — | — | CN | disclosed |