Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.45 |
| ▸ | IDH1 | O75874 | 5/20 | 0.45 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19751545 | 0.81 | DAO (0.58) | IDH1KDM4EGALR3ALDH1A1GAA | |
| SCHEMBL7264461 | 0.81 | IDH1 (0.51) | CYP19A1CHEK1IDH1KDM4EGALR3 | |
| SCHEMBL10691248 | 0.81 | DAO (0.58) | IDH1 | |
| SCHEMBL8139952 | 0.81 | FLT3 (0.49) | CHEK1IDH1CA2GAANPSR1 | |
| SCHEMBL22185219 | 0.81 | BRD4 (0.54) | IMPDH2IMPDH1CYP19A1CHEK1IDH1 | |
| SCHEMBL10690995 | 0.79 | KDM4E (0.43) | IDH1KDM4EGALR3ALDH1A1GAA | |
| SCHEMBL1903750 | 0.79 | BRD4 (0.55) | CHEK1IDH1CA1CA2KDM4E | |
| SCHEMBL29890500 | 0.79 | BRD4 (0.55) | CHEK1IDH1CA1CA2KDM4E | |
| SCHEMBL7499153 | 0.78 | IDH1 (0.58) | IDH1CA2KDM4EALDH1A1GAA | |
| SCHEMBL7501391 | 0.78 | IDH1 (0.55) | IDH1KDM4EGALR3ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115003665-A | Substituted aminoquinolones as immunoactive DGK alpha inhibitors | 拜耳公司 | 2022-09-02 | — | — | CN | disclosed |