Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.72 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | QDPR | P09417 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23411573 | 1.00 | HTR3A (0.72) | HTR3ASLC18A3SIGMAR1HTR2CQDPR | |
| SCHEMBL12536782 | 0.96 | HTR3A (0.66) | HTR3ASLC18A3SIGMAR1 | |
| SCHEMBL187003 | 0.92 | HTR3A (0.77) | HTR3ASLC18A3SIGMAR1HTR2CQDPR | |
| Hydrochloric Acid SCHEMBL557429 | 0.90 | HTR3A (0.74) | HTR3ASLC18A3SIGMAR1HTR2CQDPR | |
| Hydrochloric Acid SCHEMBL23411632 | 0.88 | HTR3A (0.71) | HTR3ASLC18A3SIGMAR1HTR2CQDPR | |
| SCHEMBL16446343 | 0.86 | HTR3A (0.81) | HTR3A | |
| SCHEMBL308190 | 0.86 | HTR3A (0.81) | HTR3A | |
| SCHEMBL16446546 | 0.86 | HTR3A (0.81) | HTR3A | |
| Hydrochloric Acid SCHEMBL2884603 | 0.85 | HTR3A (0.79) | HTR3A | |
| SCHEMBL447190 | 0.84 | HTR3A (1.00) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119564686-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119523983-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119424429-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-115003665-B | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-115003665-A | Substituted aminoquinolones as immunoactive DGK alpha inhibitors | 拜耳公司 | 2022-09-02 | — | — | CN | disclosed |