Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.42 |
| ▸ | MAT2A | P31153 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23410193 | 1.00 | CYP2C19 (0.48) | CYP2C19CYP11B2CYP11B1MAOAGSK3B | |
| SCHEMBL25389422 | 0.89 | GSK3B (0.45) | CYP11B2CYP11B1MAOAGSK3BMEN1 | |
| SCHEMBL29892074 | 0.85 | CYP11B2 (0.49) | CYP2C19CYP11B2CYP11B1MAOAMAT2A | |
| SCHEMBL23410213 | 0.85 | CYP11B2 (0.49) | CYP2C19CYP11B2CYP11B1MAOAMAT2A | |
| SCHEMBL29891687 | 0.84 | LMNA (0.41) | MAOAMEN1KMT2AKDM4EGRM4 | |
| SCHEMBL23410160 | 0.84 | LMNA (0.41) | MAOAMEN1KMT2AKDM4EGRM4 | |
| SCHEMBL29891499 | 0.83 | ATM (0.46) | HIF1AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL23410287 | 0.83 | ATM (0.46) | HIF1AMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL23410062 | 0.83 | EGLN1 (0.53) | GSK3BMEN1MAPK1KMT2AKDM4E | |
| SCHEMBL30608116 | 0.83 | CYP11B2 (0.47) | CYP2C19CYP11B2CYP11B1MAOAMAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119564686-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119523983-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119424429-A | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-115003665-B | DGK alpha inhibitors as immune activation substituted aminoquinolones of (2) | 拜耳公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-115003665-A | Substituted aminoquinolones as immunoactive DGK alpha inhibitors | 拜耳公司 | 2022-09-02 | — | — | CN | disclosed |