Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1376567 | 0.91 | CYP1A2 (0.38) | CYP1A2CYP2A6TSHRNPSR1ALDH1A1 | |
| SCHEMBL13775286 | 0.89 | ESR1 (0.33) | CYP1A2CYP2A6TSHRNPSR1PKM | |
| SCHEMBL2323159 | 0.89 | HPRT1 (0.38) | CYP1A2CYP2A6TSHRHTTNPSR1 | |
| SCHEMBL29555328 | 0.89 | HPRT1 (0.38) | CYP1A2CYP2A6TSHRHTTNPSR1 | |
| SCHEMBL13775184 | 0.88 | HTT (0.34) | CYP1A2CYP2A6TSHRHTTNPSR1 | |
| SCHEMBL13024029 | 0.86 | HTT (0.46) | CYP1A2CYP2A6TSHRHTTNPSR1 | |
| SCHEMBL20115617 | 0.86 | CYP1A2 (0.39) | CYP1A2CYP2A6NPSR1MAPTS1PR1 | |
| SCHEMBL18978244 | 0.86 | S1PR1 (0.36) | CYP1A2NPSR1L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL12887593 | 0.85 | CYP2A6 (0.39) | CYP1A2CYP2A6TSHRHTTNPSR1 | |
| SCHEMBL23334227 | 0.84 | MAPT (0.37) | CYP1A2CYP2A6TSHRNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058478-B2 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-11-15 | — | — | US | disclosed |
| US-8058478-B2 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-11-15 | — | — | US | disclosed |
| US-20110034733-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-02-10 | — | — | US | disclosed |
| US-20110034733-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2011-02-10 | — | — | US | disclosed |
| US-7816017-B2 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-10-19 | — | — | US | disclosed |
| US-7816017-B2 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2010-10-19 | — | — | US | disclosed |
| US-20100181555-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENT DEVICE, AND ORGANIC ELECTROLUMINESCENT DISPLAY | IDEMITSU KOSAN CO., LTD. (JP) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034733-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | TYR, DDC, EML4 | CYP1A2 1093/4885CYP2A6 2958/4885TSHR 4212/4885 |
| US-20100181555-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENT DEVICE, AND ORGANIC ELECTROLUMINESCENT DISPLAY | AFF4, CLIC4, L1CAM | CYP1A2 1454/4885CYP2A6 4584/4885TSHR 1322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.