SCHEMBL2989276

SCHEMBL2989276

CC(C)C1CCCCC1C1CCCC2CCCC21

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.34
TRPM8 Q7Z2W7 2/20 0.34
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9517715 1.00 TRPA1 (0.34) TRPA1TRPM8ALDH1A1
SCHEMBL2992554 0.93 TRPA1 (0.33) TRPA1TRPM8
SCHEMBL3360230 0.91 TRPA1 (0.37) TRPA1TRPM8ALDH1A1
SCHEMBL23914125 0.88 TRPA1 (0.38) TRPA1TRPM8
SCHEMBL18950740 0.81 TRPA1 (0.37) TRPA1TRPM8
SCHEMBL2985890 0.81 CYP1A2 (0.33)
SCHEMBL2957042 0.79
SCHEMBL3003655 0.77 TRPA1 (0.34) TRPA1TRPM8ALDH1A1
SCHEMBL1499973 0.77 ALDH1A1 (0.50) ALDH1A1
SCHEMBL2989991 0.77 MEN1 (0.32) TRPA1TRPM8ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed