Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.59 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | DDO | Q99489 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13802346 | 0.85 | BRD4 (0.59) | BRD4DAOHRH4LMNAHPGD | |
| SCHEMBL16627567 | 0.81 | METAP2 (0.46) | DAODDOMETAP2HRH4TP53 | |
| SCHEMBL15478601 | 0.81 | DAO (0.68) | BRD4DAODDOLMNAHPGD | |
| SCHEMBL25317005 | 0.79 | ALDH1A1 (0.49) | DAOLMNAHPGDMAPTGRIN2D | |
| SCHEMBL15690449 | 0.78 | DAO (0.64) | DAODDOMETAP2 | |
| SCHEMBL1438376 | 0.78 | BRD4 (0.59) | BRD4DAODDOTYMSGRIN2D | |
| SCHEMBL1038241 | 0.78 | BRD4 (0.59) | BRD4DAODDOHRH4HPGD | |
| SCHEMBL1709827 | 0.78 | BRD4 (0.59) | BRD4DAODDOHRH4HPGD | |
| SCHEMBL12970589 | 0.78 | DAO (0.64) | BRD4DAODDOTYMSGRIN2D | |
| SCHEMBL4388117 | 0.78 | DAO (0.64) | BRD4DAODDOLMNAGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |