Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 4/20 | 0.48 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 4/20 | 0.46 |
| ▸ | IL1RN | P18510 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38664916 | 0.94 | BACE1 (0.49) | NAALAD2BACE1BACE2OPRD1OPRM1 | |
| SCHEMBL29893008 | 0.91 | BACE1 (0.49) | NAALAD2BACE1BACE2OPRD1 | |
| SCHEMBL30317559 | 0.91 | NAALAD2 (0.60) | NAALAD2MMEENPEP | |
| SCHEMBL30445027 | 0.90 | NAALAD2 (0.54) | NAALAD2BACE1BACE2MME | |
| SCHEMBL29464215 | 0.86 | NAALAD2 (0.57) | NAALAD2BACE1BACE2MMEIL1RN | |
| SCHEMBL30123048 | 0.85 | MME (0.47) | NAALAD2OPRD1OPRM1MMEENPEP | |
| SCHEMBL29528229 | 0.85 | LNPEP (0.50) | OPRD1OPRM1SLC6A2MMEERAP2 | |
| SCHEMBL31257017 | 0.85 | SLC6A2 (0.59) | OPRD1OPRM1SLC6A2MMEOPRK1 | |
| SCHEMBL31208252 | 0.84 | BACE1 (0.63) | BACE1BACE2OPRD1OPRM1OPRK1 | |
| SCHEMBL11886066 | 0.84 | NAALAD2 (0.66) | NAALAD2ERAP2ENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158448-A1 | MULTIVALENT NANO-'SELF' PEPTIDES AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-05-16 | — | — | US | claimed |
| WO-2022178263-A1 | MULTIVALENT NANO-'SELF' PEPTIDES AND USES THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2022-08-25 | — | — | WO | claimed |
| US-20240158448-A1 | MULTIVALENT NANO-'SELF' PEPTIDES AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-05-16 | — | — | US | disclosed |
| WO-2022178263-A1 | MULTIVALENT NANO-'SELF' PEPTIDES AND USES THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2022-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158448-A1 | MULTIVALENT NANO-'SELF' PEPTIDES AND USES THEREOF | CD47, CD68, CHERP | NAALAD2 2786/4885BACE1 1571/4885BACE2 2269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.