Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1691989 | 0.96 | CYP3A4 (0.54) | CYP3A4TSHRACHELMNATEAD4 | |
| Ammonia Solution, Strong SCHEMBL8859771 | 0.93 | CYP3A4 (0.52) | CYP3A4TSHRACHELMNATEAD4 | |
| P-Cresol SCHEMBL15546465 | 0.86 | ACHE (0.50) | CYP3A4TSHRACHELMNAMEN1 | |
| SCHEMBL6692402 | 0.82 | CYP3A4 (0.54) | CYP3A4TSHRACHELMNATEAD4 | |
| SCHEMBL258632 | 0.81 | CYP3A4 (0.58) | CYP3A4TSHRACHELMNATEAD4 | |
| SCHEMBL30320737 | 0.81 | MEN1 (0.46) | CYP3A4TSHRACHELMNAMEN1 | |
| SCHEMBL869948 | 0.78 | TSHR (0.50) | CYP3A4TSHRACHELMNATEAD4 | |
| Zinc Ion SCHEMBL2973913 | 0.77 | SRC (0.43) | TSHRLMNAMEN1KMT2ATDP1 | |
| Zinc Ion SCHEMBL7267876 | 0.77 | CYP3A4 (0.54) | CYP3A4TSHRACHELMNATEAD4 | |
| Zinc Ion SCHEMBL940367 | 0.76 | CYP3A4 (0.52) | CYP3A4TSHRACHELMNATEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786058-B2 | Rolling device employing lubricating grease composition and electric power steering apparatus employing the rolling device | JTEKT CORPORATION (JP) | 2010-08-31 | — | — | US | disclosed |
| US-20090065287-A1 | ROLLING DEVICE EMPLOYING LUBRICATING GREASE COMPOSITION AND ELECTRIC POWER STEERING APPARATUS EMPLOYING THE ROLLING DEVICE | JTEKT CORPORATION (JP) | 2009-03-12 | — | — | US | disclosed |