Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791725 | 0.72 | ALDH1A1 (0.46) | TDP1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL4511748 | 0.70 | ALDH1A1 (0.50) | TDP1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL29711837 | 0.70 | ALDH1A1 (0.50) | TDP1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL30149937 | 0.69 | MAPK8 (0.50) | TDP1HSD17B10CASP1MAPK10CASP7 | |
| SCHEMBL3337856 | 0.66 | KDM4E (0.46) | TDP1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL29284760 | 0.66 | HSD17B10 (0.46) | TDP1HSD17B10CASP1MAPK10CASP7 | |
| SCHEMBL2947750 | 0.65 | KDM4E (0.46) | TDP1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL4931034 | 0.64 | SMN1; SMN2 (0.47) | TDP1HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9216927 | 0.63 | ALDH1A1 (0.50) | TDP1HSD17B10CASP1MAPK10CASP7 | |
| SCHEMBL31612341 | 0.63 | HSD17B10 (0.42) | TDP1HSD17B10CASP1MAPK10CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |