Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753350 | 0.87 | HTR2C (0.67) | HTR2CPIK3R1PIK3CAL3MBTL1 | |
| SCHEMBL7327979 | 0.81 | HTR2C (0.70) | HTR2CPIK3R1PIK3CAL3MBTL1TSHR | |
| SCHEMBL29893322 | 0.80 | HTR2C (0.44) | HTR2CPIK3R1PIK3CAL3MBTL1CYP3A4 | |
| SCHEMBL29894392 | 0.80 | HTR2C (0.44) | HTR2CPIK3R1PIK3CAL3MBTL1 | |
| SCHEMBL30753359 | 0.71 | HTR2C (0.47) | HTR2CPIK3R1PIK3CAL3MBTL1NUDT1 | |
| SCHEMBL27077423 | 0.71 | HTR2C (0.37) | HTR2CPIK3R1PIK3CAKIF18A | |
| SCHEMBL31291368 | 0.70 | HTR2C (0.56) | HTR2CPIK3R1PIK3CAL3MBTL1NUDT1 | |
| SCHEMBL5477688 | 0.70 | NUDT1 (0.55) | HTR2CPIK3R1PIK3CAL3MBTL1NUDT1 | |
| SCHEMBL103894 | 0.69 | HTR2C (0.53) | HTR2CPIK3R1PIK3CAL3MBTL1NUDT1 | |
| SCHEMBL30856617 | 0.67 | HTR2C (0.42) | HTR2CPIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |