Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29893256 | 0.80 | HTR2C (0.68) | HTR2CPIK3R1PIK3CAL3MBTL1CYP3A4 | |
| SCHEMBL27077423 | 0.77 | HTR2C (0.37) | HTR2CPIK3R1PIK3CA | |
| SCHEMBL29894392 | 0.76 | HTR2C (0.44) | HTR2CPIK3R1PIK3CAL3MBTL1 | |
| SCHEMBL30753359 | 0.71 | HTR2C (0.47) | HTR2CPIK3R1PIK3CAL3MBTL1 | |
| SCHEMBL27225403 | 0.68 | NUDT1 (0.37) | HTR2CPIK3R1PIK3CA | |
| SCHEMBL30753350 | 0.68 | HTR2C (0.67) | HTR2CPIK3R1PIK3CAL3MBTL1 | |
| SCHEMBL15760259 | 0.66 | HRH4 (0.46) | HTR2CPIK3R1PIK3CA | |
| SCHEMBL31038551 | 0.66 | HTR2C (0.41) | HTR2CPIK3R1PIK3CA | |
| SCHEMBL30856617 | 0.64 | HTR2C (0.42) | HTR2CPIK3R1PIK3CA | |
| SCHEMBL16094859 | 0.61 | PIK3CA (0.60) | HTR2CPIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |