Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24941095 | 1.00 | ADORA3 (0.44) | ADORA3ADORA2AADORA1ADORA2BALOX15 | |
| SCHEMBL29893560 | 0.84 | ADORA2A (0.52) | ADORA3ADORA2AADORA1ADORA2BALOX15 | |
| SCHEMBL24941203 | 0.84 | ADORA2A (0.52) | ADORA3ADORA2AADORA1ADORA2BALOX15 | |
| SCHEMBL24941090 | 0.80 | ADORA1 (0.35) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL24941214 | 0.74 | PI4KA (0.32) | — | |
| SCHEMBL22579677 | 0.73 | ADORA3 (0.45) | ADORA3ADORA2AADORA1ADORA2BALOX15 | |
| SCHEMBL20180024 | 0.72 | ADORA3 (0.72) | ADORA3ADORA2AADORA1ADORA2BALOX15 | |
| SCHEMBL24672312 | 0.72 | ADORA3 (0.47) | ADORA3ADORA2AADORA1ADORA2BALOX15 | |
| SCHEMBL30008091 | 0.72 | ADORA3 (0.47) | ADORA3ADORA2AADORA1ADORA2BALOX15 | |
| SCHEMBL23907542 | 0.71 | NT5E (0.44) | ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945578-A | Compounds as CD73 inhibitors | 博奥阿迪斯生物科技公司 | 2022-08-26 | — | — | CN | disclosed |