SCHEMBL29893565

SCHEMBL29893565

Bc1cn(C(=O)OC(C)(C)C)c2c(C#N)cccc12

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ ELANE P08246 7/20 0.37
▸ POLB P06746 2/20 0.36
▸ GPR119 Q8TDV5 1/20 0.35
▸ BCHE P06276 1/20 0.35
▸ MAPT P10636 1/20 0.34
▸ IMPDH2 P12268 2/20 0.33
▸ STAT3 P40763 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ BRD4 O60885 1/20 0.32
▸ CREBBP Q92793 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19100201 0.85 L3MBTL1 (0.37) L3MBTL1ELANEPOLBGPR119BCHE
SCHEMBL26615777 0.84 L3MBTL1 (0.39) L3MBTL1ELANEPOLBGPR119BCHE
SCHEMBL24721570 0.81 L3MBTL1 (0.39) L3MBTL1GPR119BCHEMEN1KMT2A
SCHEMBL29361217 0.78 L3MBTL1 (0.33) L3MBTL1ELANEPOLBGPR119BCHE
SCHEMBL25028610 0.78 L3MBTL1 (0.33) L3MBTL1ELANEPOLBGPR119BCHE
SCHEMBL19100666 0.75 ACLY (0.44) GPR119BCHEMEN1TSHRKMT2A
SCHEMBL31186267 0.75 L3MBTL1 (0.55) L3MBTL1ELANEPOLBMAPTIMPDH2
SCHEMBL19100397 0.74 AAK1 (0.41) ELANEPOLBGPR119
SCHEMBL14222808 0.74 L3MBTL1 (0.57) L3MBTL1BCHEMEN1KMT2ABRD4
SCHEMBL29005571 0.73 ELANE (0.33) L3MBTL1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204235-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. (US) 2022-09-29 — — WO disclosed
US-20220306609-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES, INC. 2022-09-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220306609-A1 BICYCLIC COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS AR, FSHR, NCOA3 L3MBTL1 4313/4885ELANE 3737/4885POLB 1197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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