Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941823 | 0.93 | ADRB2 (0.40) | ADRB2ALDH1A1KMT2AMEN1KCNH2 | |
| SCHEMBL29941704 | 0.90 | ADRB2 (0.39) | ADRB2ALDH1A1KMT2AMEN1EPAS1 | |
| SCHEMBL29893684 | 0.88 | ADRB2 (0.39) | ADRB2ALDH1A1KMT2AMEN1KCNH2 | |
| SCHEMBL28889200 | 0.87 | ADRB2 (0.41) | ADRB2ALDH1A1KMT2AMEN1KCNH2 | |
| SCHEMBL28889188 | 0.85 | ADRB2 (0.39) | ADRB2ALDH1A1KMT2AMEN1KCNH2 | |
| SCHEMBL28889319 | 0.85 | ADRB2 (0.41) | ADRB2ALDH1A1KMT2AMEN1EPAS1 | |
| SCHEMBL28889330 | 0.85 | ALDH1A1 (0.44) | ADRB2ALDH1A1KMT2AMEN1KCNH2 | |
| SCHEMBL28889286 | 0.84 | ADRB2 (0.36) | ADRB2ALDH1A1KMT2AMEN1KCNH2 | |
| SCHEMBL29941803 | 0.82 | HDAC4 (0.42) | ADRB2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL29941794 | 0.82 | ADRB2 (0.38) | ADRB2ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215862-A | Pyrimidone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-21 | — | — | CN | disclosed |