Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | COMT | P21964 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1202856 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL1005723 | 0.86 | SMN1; SMN2 (0.41) | SMN1; SMN2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL1056662 | 0.86 | MEN1 (0.45) | SMN1; SMN2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL1202303 | 0.86 | KDM4E (0.42) | SMN1; SMN2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL26988941 | 0.84 | PDGFRB (0.41) | SMN1; SMN2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL30722742 | 0.84 | PDGFRB (0.41) | SMN1; SMN2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL1202724 | 0.83 | ALDH1A1 (0.46) | SMN1; SMN2KMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL31423850 | 0.80 | PKM (0.45) | CES2CES1PKMTTRTDP1 | |
| SCHEMBL1202494 | 0.80 | PKM (0.45) | CES2CES1PKMTTRTDP1 | |
| SCHEMBL7009698 | 0.78 | PDGFRB (0.41) | SMN1; SMN2PDGFRBFGFR1PDGFRAFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115023419-A | Cereblon-bound piperidine-2, 6-diones and methods of use thereof | 凯普托尔治疗学股份有限公司 | 2022-09-06 | — | — | CN | disclosed |