Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2146479 | 0.77 | CA12 (0.44) | PDE4DCYP3A4HIF1AEPAS1ALDH1A1 | |
| SCHEMBL30876198 | 0.77 | CA12 (0.44) | PDE4DCYP3A4HIF1AEPAS1ALDH1A1 | |
| SCHEMBL31345843 | 0.77 | PTGES (0.51) | PDE4DCYP3A4HIF1AALDH1A1LMNA | |
| SCHEMBL29390169 | 0.76 | HIF1A (0.60) | PDE4DCYP3A4HIF1AEPAS1ALDH1A1 | |
| Soulattrolide SCHEMBL2040583 | 0.76 | ALDH1A1 (0.67) | PDE4DCYP3A4HIF1AEPAS1ALDH1A1 | |
| Soulattrolide SCHEMBL6731413 | 0.76 | ALDH1A1 (0.67) | PDE4DCYP3A4HIF1AEPAS1ALDH1A1 | |
| Soulattrolide SCHEMBL8698180 | 0.76 | ALDH1A1 (0.67) | PDE4DCYP3A4HIF1AEPAS1ALDH1A1 | |
| SCHEMBL8702867 | 0.75 | ALDH1A1 (0.45) | PDE4DCYP3A4HIF1AEPAS1ALDH1A1 | |
| SCHEMBL8698429 | 0.75 | ALDH1A1 (0.45) | PDE4DCYP3A4HIF1AEPAS1ALDH1A1 | |
| SCHEMBL13016723 | 0.74 | ALDH1A1 (0.40) | PDE4DCYP3A4ALDH1A1MAPK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590724-B | 4-arylpyran derivative containing aryl urea and application thereof | 陕西理工大学 | 2022-09-30 | — | — | CN | disclosed |