Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.71 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13035333 | 0.83 | CYP2A6 (1.00) | CYP2A6CHEK2CYP2B6CYP3A4CYP2C9 | |
| SCHEMBL13035338 | 0.81 | CYP2A6 (1.00) | CYP2A6CYP11B1CYP11B2CHEK2CYP2B6 | |
| SCHEMBL2983844 | 0.81 | CYP11B2 (0.61) | CYP11B1CYP11B2MAP4K4PIK3CG | |
| SCHEMBL4201985 | 0.80 | CYP2A6 (0.50) | CYP2A6CHEK2CYP2B6CYP3A4CYP2C9 | |
| SCHEMBL4199347 | 0.79 | TDP2 (0.58) | CYP2A6CHEK2CYP2B6CYP3A4CYP2C9 | |
| SCHEMBL30726373 | 0.78 | CYP11B2 (0.56) | CYP2A6CYP11B1CYP11B2MAP4K4 | |
| SCHEMBL1651440 | 0.78 | CYP11B2 (0.56) | CYP2A6CYP11B1CYP11B2MAP4K4 | |
| SCHEMBL28312712 | 0.77 | CYP2A6 (0.44) | CYP2A6CYP2B6CYP2E1 | |
| SCHEMBL17116680 | 0.77 | CYP11B2 (0.58) | CYP11B1CYP11B2MAP4K4PIK3CG | |
| SCHEMBL17116617 | 0.76 | CYP11B2 (0.62) | CYP11B1CYP11B2MAP4K4PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115710219-B | Method for preparing meta-cyano-substituted pyridine compound | 南开大学 | 2024-12-03 | — | — | CN | disclosed |
| CN-115710219-A | Method for preparing meta cyano-substituted pyridine compound | 南开大学 | 2023-02-24 | — | — | CN | disclosed |
| US-7781591-B2 | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH LLC (US) | 2010-08-24 | — | — | US | disclosed |
| US-20070287708-A1 | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH LLC | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287708-A1 | Substituted 3-cyanopyridines as protein kinase inhibitors | CNKSR1, MAP3K1, MAP3K7 | CYP2A6 2820/4885CYP11B1 1865/4885CYP11B2 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.