Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | BCL2 | P10415 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28604647 | 0.89 | GPR119 (0.46) | IDO1GPR119AAK1JAK2MEN1 | |
| SCHEMBL28607177 | 0.89 | GPR119 (0.46) | IDO1GPR119AAK1JAK2CYP17A1 | |
| SCHEMBL28604646 | 0.89 | GPR119 (0.46) | IDO1GPR119AAK1JAK2MEN1 | |
| SCHEMBL28614617 | 0.88 | GPR119 (0.45) | IDO1GPR119AAK1MEN1KMT2A | |
| SCHEMBL28617686 | 0.80 | IDO1 (0.38) | IDO1GPR119JAK2BCL2CYP17A1 | |
| SCHEMBL28605926 | 0.80 | MEN1 (0.46) | IDO1GPR119AAK1JAK2CYP17A1 | |
| SCHEMBL28603103 | 0.80 | IDO1 (0.41) | IDO1GPR119AAK1JAK2BCL2 | |
| SCHEMBL22125838 | 0.79 | IDO1 (0.41) | IDO1GPR119JAK2BCL2CYP17A1 | |
| SCHEMBL28602379 | 0.79 | GPR119 (0.44) | IDO1GPR119JAK2CYP17A1MEN1 | |
| SCHEMBL28609015 | 0.79 | HDAC8 (0.53) | BCL2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11377425-B1 | Small molecule modulators of IL-17 | LEO PHARMA A/S (DK) | 2022-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11377425-B1 | Small molecule modulators of IL-17 | IL17A, IL15, IL2 | IDO1 594/4885GPR119 2796/4885AAK1 2606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.