Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MGLL | Q99685 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896187 | 1.00 | MEN1 (0.56) | MEN1KMT2AMGLLFAAHTP53 | |
| SCHEMBL19306584 | 1.00 | MEN1 (0.56) | MEN1KMT2AMGLLFAAHTP53 | |
| SCHEMBL19306610 | 0.87 | MAPT (0.59) | MEN1KMT2AMGLLFAAHKDM4E | |
| SCHEMBL29896183 | 0.87 | MAPT (0.59) | MEN1KMT2AMGLLFAAHKDM4E | |
| SCHEMBL29896191 | 0.85 | MEN1 (0.58) | MEN1KMT2AMGLLFAAHKDM4E | |
| SCHEMBL19306585 | 0.85 | MEN1 (0.58) | MEN1KMT2AMGLLFAAHKDM4E | |
| SCHEMBL21689064 | 0.85 | MEN1 (0.53) | MEN1KMT2AKDM4EGAANPC1 | |
| SCHEMBL1115881 | 0.80 | CYP1A2 (0.64) | MEN1KMT2AMGLLAKR1C3KDM4E | |
| SCHEMBL4599121 | 0.78 | ALDH1A1 (0.65) | MEN1KMT2AMGLLKDM4ESMN1; SMN2 | |
| SCHEMBL9760661 | 0.77 | MAPT (0.77) | MEN1KMT2AMGLLFAAHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115227685-A | DNP and DNP prodrug treatment of diseases | 米托充制药公司 | 2022-10-25 | — | — | CN | disclosed |