Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MGLL | Q99685 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | PHGDH | O43175 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1735252 | 0.84 | ADORA2A (0.51) | ALDH1A1MAPTMGLLRAB9ANPSR1 | |
| SCHEMBL1115881 | 0.83 | CYP1A2 (0.64) | KDM4EMGLLRAB9AMEN1KMT2A | |
| SCHEMBL10458761 | 0.82 | GAA (0.63) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2635694 | 0.81 | FKBP1A (0.66) | ALDH1A1MAPTKDM4EMGLLRAB9A | |
| SCHEMBL5651256 | 0.80 | RAB9A (0.63) | KDM4EHSD17B10MGLLRAB9APHGDH | |
| SCHEMBL19306584 | 0.78 | MEN1 (0.56) | ALDH1A1MAPTKDM4EMGLLRAB9A | |
| SCHEMBL29896187 | 0.78 | MEN1 (0.56) | ALDH1A1MAPTKDM4EMGLLRAB9A | |
| SCHEMBL29896186 | 0.78 | MEN1 (0.56) | ALDH1A1MAPTKDM4EMGLLRAB9A | |
| SCHEMBL28372646 | 0.78 | EPHX1 (0.68) | ALDH1A1EPHX1KDM4EHSD17B10RAB9A | |
| SCHEMBL4598628 | 0.78 | EPHX1 (0.68) | EPHX1KDM4EHSD17B10RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910320-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-04-16 | — | — | EP | claimed |
| WO-2007011065-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-01-25 | — | — | WO | claimed |
| CN-118251382-A | Catalytic hydrogenation of aromatic nitro compounds | 豪夫迈·罗氏有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-105793430-B | Process for the preparation of chiral 2-arylmorpholines | 豪夫迈·罗氏有限公司 | 2020-03-03 | — | — | CN | disclosed |
| EP-1910320-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007011065-A2 | INTERMEDIATE COMPOUND FOR SYNTHESIZING PHARMACEUTICAL AGENT AND PRODUCTION METHOD THEREOF | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-01-25 | — | — | WO | disclosed |