Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.68 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.63 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MITF | O75030 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896251 | 1.00 | TOP2A (0.68) | TOP2AAGTR1HKDC1HTTSMN1; SMN2 | |
| SCHEMBL13522803 | 1.00 | TOP2A (0.68) | TOP2AAGTR1HKDC1HTTSMN1; SMN2 | |
| SCHEMBL31690656 | 0.91 | AGTR1 (0.70) | TOP2AAGTR1HKDC1HTTSMN1; SMN2 | |
| SCHEMBL1024423 | 0.91 | TOP2A (0.75) | TOP2AAGTR1HKDC1HTTSMN1; SMN2 | |
| SCHEMBL13522778 | 0.85 | TOP2A (0.70) | TOP2AAGTR1HKDC1HTTSMN1; SMN2 | |
| SCHEMBL3133142 | 0.82 | AGTR1 (0.67) | AGTR1HKDC1HTTSMN1; SMN2LMNA | |
| SCHEMBL13522802 | 0.82 | AGTR1 (0.67) | AGTR1HKDC1HTTSMN1; SMN2LMNA | |
| SCHEMBL12680561 | 0.82 | AGTR1 (0.55) | TOP2AAGTR1HKDC1HTTSMN1; SMN2 | |
| SCHEMBL12680566 | 0.82 | AGTR1 (0.55) | TOP2AAGTR1HKDC1HTTSMN1; SMN2 | |
| SCHEMBL7086491 | 0.82 | AGTR1 (0.62) | TOP2AAGTR1HKDC1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957294-A | Preparation method and application of N-heterocyclic thiosemicarbazide mixed-valence copper complex | 桂林医学院 | 2022-08-30 | — | — | CN | claimed |
| CN-114957294-A | Preparation method and application of N-heterocyclic thiosemicarbazide mixed-valence copper complex | 桂林医学院 | 2022-08-30 | — | — | CN | disclosed |