Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.67 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.61 |
| ▸ | CTSL | P07711 | 5/20 | 0.57 |
| ▸ | CTSB | P07858 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133142 | 1.00 | AGTR1 (0.67) | AGTR1HKDC1CTSLCTSBRAB9A | |
| SCHEMBL29402921 | 0.91 | AGTR1 (0.53) | AGTR1HKDC1CTSLCTSBRAB9A | |
| SCHEMBL800985 | 0.91 | AGTR1 (0.53) | AGTR1HKDC1CTSLCTSBRAB9A | |
| SCHEMBL31690656 | 0.88 | AGTR1 (0.70) | AGTR1HKDC1RAB9ANCOA3NPC1 | |
| SCHEMBL29896251 | 0.82 | TOP2A (0.68) | AGTR1HKDC1RAB9ANCOA3NPC1 | |
| SCHEMBL29896301 | 0.82 | TOP2A (0.68) | AGTR1HKDC1RAB9ANCOA3NPC1 | |
| SCHEMBL13522803 | 0.82 | TOP2A (0.68) | AGTR1HKDC1RAB9ANCOA3NPC1 | |
| Benzophenone-Thiosemicarbazone SCHEMBL17666878 | 0.82 | CTSL (0.80) | CTSLCTSBCTSKATMMETTL3 | |
| SCHEMBL7086790 | 0.81 | AGTR1 (0.62) | AGTR1HKDC1RAB9ANCOA3NPC1 | |
| SCHEMBL7086491 | 0.81 | AGTR1 (0.62) | AGTR1HKDC1RAB9ANCOA3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010000008-A1 | THIOSEMICARBAZONE COMPOUNDS AND USE THEREOF | RICHARDSON DESI RAYMOND (AU) | 2010-01-07 | — | — | WO | disclosed |