SCHEMBL2989673

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2996285	0.92	EGFR (0.71)	EGFRERBB2SRCKITERBB3
	SCHEMBL2989664	0.84	EGFR (1.00)	EGFRERBB2SRCKITERBB3
	SCHEMBL2991327	0.83	EGFR (0.53)	EGFRERBB2SRCKDRRET
	SCHEMBL7847668	0.82	EGFR (0.66)	EGFRERBB2SRCERBB4KDR
	SCHEMBL2985880	0.81	FBP1 (0.54)	EGFRSRCKDRBRAF
	SCHEMBL7057985	0.78	EGFR (1.00)	EGFRERBB2SRCKITERBB3
	SCHEMBL26055531	0.77	EGFR (0.85)	EGFRERBB2SRCKITERBB3
	SCHEMBL26055582	0.76	EGFR (0.81)	EGFRERBB2SRCKITERBB3
	SCHEMBL1418291	0.76	EGFR (0.84)	EGFRERBB2SRCKITERBB3
	SCHEMBL26055584	0.76	EGFR (0.73)	EGFRERBB2SRCKITERBB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.