SCHEMBL298975

SCHEMBL298975

Cc1cc(C(C)Cc2ccc(CC(C)c3ccc(O)c(C)c3)cc2)ccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.58
ESR2 Q92731 6/20 0.58
ALOX15 P16050 4/20 0.44
AR P10275 4/20 0.44
ALOX12 P18054 3/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 3/20 0.44
HSD17B10 Q99714 3/20 0.44
TP53 P04637 3/20 0.44
NR3C1 P04150 3/20 0.44
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44
CYP3A4 P08684 2/20 0.44
MAPK1 P28482 2/20 0.44
RECQL P46063 2/20 0.44
KMT2A Q03164 2/20 0.44
HIF1A Q16665 2/20 0.44
USP2 O75604 2/20 0.44
PGR P06401 2/20 0.44
TDP1 Q9NUW8 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27223872 0.95 ESR1 (0.55) ESR1ESR2ALOX15ARALOX12
SCHEMBL28481915 0.91 ESR1 (0.49) ESR1ESR2ALOX15ALDH1A1HPGD
SCHEMBL30374755 0.89 ESR1 (0.58) ESR1ESR2ALOX15ARALOX12
SCHEMBL697803 0.88 ESR1 (0.44) ESR1ESR2ALOX15ARALOX12
SCHEMBL3234487 0.87 ESR1 (0.45) ESR1ESR2ALOX15ARALOX12
SCHEMBL5137345 0.84 ESR1 (0.52) ESR1ESR2ALOX15ARALOX12
SCHEMBL29888554 0.84 ESR1 (0.68) ESR1ESR2ALOX15ARALOX12
SCHEMBL3234408 0.84 ESR1 (0.68) ESR1ESR2ALOX15ARALOX12
SCHEMBL3237259 0.84 ESR1 (0.47) ESR1ESR2ALOX15ARALOX12
SCHEMBL4601360 0.82 USP2 (0.41) ESR1ESR2ALOX15ARALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090163692-A1 AROMATIC POLYETHERS GENERAL ELECTRIC COMPANY (US) 2009-06-25 US claimed
EP-1504048-B1 METHOD OF PREPARING POLYESTERCARBONATES GEN ELECTRIC (US) 2007-11-21 EP claimed
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
EP-1543061-B1 METHOD OF PREPARING TRANSPARENT SILICONE-CONTAINING COPOLYCARBONATES GEN ELECTRIC (US) 2006-08-30 EP claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
US-6833422-B2 Interfacial polymerization of polycarbonates with polysiloxanes, then endcapping to form haze-free polycarbonatepolysiloxane copolymers GENERAL ELECTRIC COMPANY 2004-12-21 US claimed
US-6780961-B2 CONVERTING OLIGOMERIC CHLOROFORMATES TO HIGH MOLECULAR WEIGHT POLYCARBONATE GENERAL ELECTRIC COMPANY 2004-08-24 US claimed
US-20040077820-A1 Method of making polycarbonate GENERAL ELECTRIC COMPANY 2004-04-22 US claimed
US-20040039145-A1 Method of preparing transparent silicone-containing copolycarbonates GENERAL ELECTRIC COMPANY 2004-02-26 US claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US claimed
US-6600004-B1 Preparing polyestercarbonates is presented in which a mixture of at least one activated diaryl carbonate is reacted under melt polymerization conditions with at least one aromatic dihydroxy compound together with at least one dicarboxylic GENERAL ELECTRIC COMPANY 2003-07-29 US claimed
US-6248859-B1 CONTAINING SPIROBIINDANE UNITS; OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY 2001-06-19 US claimed
US-12509549-B2 Resin composition for laser direct structuring, molded article, and, method for manufacturing plated molded article MITSUBISHI CHEMICAL CORPORATION (JP) 2025-12-30 US disclosed
US-12139578-B2 Cover for millimeter-wave radar and millimeter-wave radar module including the same MITSUBISHI CHEMICAL CORPORATION (JP) 2024-11-12 US disclosed
US-20220372218-A1 RESIN COMPOSITION FOR LASER DIRECT STRUCTURING, MOLDED ARTICLE, AND, METHOD FOR MANUFACTURING PLATED MOLDED ARTICLE MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2022-11-24 US disclosed
US-20220363894-A1 RESIN COMPOSITION AND ELECTRONIC/ELECTRIC EQUIPMENT COMPONENT MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2022-11-17 US disclosed
US-6506871-B1 Ester interchange of bis(methyl salicyl) carbonate and bisphenol A in presence of tetrabutylphosphonium acetate catalyst GENERAL ELECTRIC COMPANY 2003-01-14 US disclosed
US-6420512-B1 SCREW EXTRUSION AND ESTER INTERCHANGE GENERAL ELECTRIC COMPANY 2002-07-16 US disclosed
US-6248859-B1 CONTAINING SPIROBIINDANE UNITS; OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY 2001-06-19 US disclosed
WO-2001002462-A1 POLYCARBONATES SUITABLE FOR USE IN OPTICAL ARTICLES GENERAL ELECTRIC COMPANY (US) 2001-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509549-B2 Resin composition for laser direct structuring, molded article, and, method for manufacturing plated molded article MECP2, POT1, EMG1 ESR1 2818/4885ESR2 2603/4885ALOX15 1817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.