SCHEMBL697803

SCHEMBL697803

Cc1cc(C(C)Cc2cccc(CC(C)c3ccc(O)c(C)c3)c2)ccc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.44
ESR2 Q92731 4/20 0.44
ALOX15 P16050 4/20 0.41
ALOX12 P18054 3/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
HSD17B10 Q99714 3/20 0.41
TP53 P04637 3/20 0.41
NR3C1 P04150 3/20 0.41
HSD17B1 P14061 3/20 0.41
HSD17B2 P37059 3/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 2/20 0.41
CYP3A4 P08684 2/20 0.41
MAPK1 P28482 2/20 0.41
RECQL P46063 2/20 0.41
KMT2A Q03164 2/20 0.41
HIF1A Q16665 2/20 0.41
USP2 O75604 2/20 0.41
PGR P06401 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28481915 0.90 ESR1 (0.49) ESR1ESR2ALOX15ALDH1A1HPGD
SCHEMBL27223872 0.90 ESR1 (0.55) ESR1ESR2ALOX15ALOX12ALDH1A1
SCHEMBL298975 0.88 ESR1 (0.58) ESR1ESR2ALOX15ALOX12ALDH1A1
SCHEMBL3175987 0.86 KDM4E (0.52) ESR1ESR2ALOX15ALOX12ALDH1A1
SCHEMBL30374755 0.84 ESR1 (0.58) ESR1ESR2ALOX15ALOX12ALDH1A1
SCHEMBL237757 0.83 ESR1 (0.43) ESR1ESR2ALOX15ALOX12ALDH1A1
SCHEMBL3234487 0.83 ESR1 (0.45) ESR1ESR2ALOX15ALOX12ALDH1A1
SCHEMBL4601360 0.81 USP2 (0.41) ESR1ESR2ALOX15ALDH1A1HPGD
SCHEMBL298394 0.81 GABRA1 (0.44) ESR1ESR2ALOX15ALOX12ALDH1A1
SCHEMBL5137345 0.80 ESR1 (0.52) ESR1ESR2ALOX15ALOX12ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 299 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
EP-1543061-B1 METHOD OF PREPARING TRANSPARENT SILICONE-CONTAINING COPOLYCARBONATES GEN ELECTRIC (US) 2006-08-30 EP claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
EP-1543061-A1 METHOD OF PREPARING TRANSPARENT SILICONE-CONTAINING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-06-22 EP claimed
US-6833422-B2 Interfacial polymerization of polycarbonates with polysiloxanes, then endcapping to form haze-free polycarbonatepolysiloxane copolymers GENERAL ELECTRIC COMPANY 2004-12-21 US claimed
US-6780961-B2 CONVERTING OLIGOMERIC CHLOROFORMATES TO HIGH MOLECULAR WEIGHT POLYCARBONATE GENERAL ELECTRIC COMPANY 2004-08-24 US claimed
US-20040077820-A1 Method of making polycarbonate GENERAL ELECTRIC COMPANY 2004-04-22 US claimed
WO-2004016674-A1 METHOD OF PREPARING TRANSPARENT SILICONE-CONTAINING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-02-26 WO claimed
US-20040039145-A1 Method of preparing transparent silicone-containing copolycarbonates GENERAL ELECTRIC COMPANY 2004-02-26 US claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US claimed
US-6248859-B1 CONTAINING SPIROBIINDANE UNITS; OPTICAL DATA STORAGE MEDIA GENERAL ELECTRIC COMPANY 2001-06-19 US claimed
US-12509549-B2 Resin composition for laser direct structuring, molded article, and, method for manufacturing plated molded article MITSUBISHI CHEMICAL CORPORATION (JP) 2025-12-30 US disclosed
US-12139578-B2 Cover for millimeter-wave radar and millimeter-wave radar module including the same MITSUBISHI CHEMICAL CORPORATION (JP) 2024-11-12 US disclosed
US-11898025-B2 Polyethylene with additives for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-02-13 US disclosed
US-11535732-B2 Polyethylene with polycarbonate-siloxane for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-12-27 US disclosed
US-5665675-A THERMAL RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-09-09 US disclosed
EP-0570186-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1997-08-13 EP disclosed
EP-0693386-B1 Aminobenzenesulfonamide derivatives as colour-developers for thermosensitive recording materials JUJO PAPER CO LTD (JP) 1997-02-05 EP disclosed
EP-0693386-A1 Aminobenzenesulfonamide derivatives as colour-developers for thermosensitive recording materials NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-01-24 EP disclosed
EP-0570186-A1 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509549-B2 Resin composition for laser direct structuring, molded article, and, method for manufacturing plated molded article MECP2, POT1, EMG1 ESR1 2818/4885ESR2 2603/4885ALOX15 1817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.