Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 9/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28481915 | 0.85 | ESR1 (0.49) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL2554988 | 0.82 | GABRA1 (0.42) | ALDH1A1PKMESR1ESR2PTGS1 | |
| SCHEMBL298975 | 0.82 | ESR1 (0.58) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL697803 | 0.81 | ESR1 (0.44) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL10940623 | 0.81 | TRPA1 (0.39) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL27223872 | 0.81 | ESR1 (0.55) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL10335147 | 0.79 | CYP3A4 (0.44) | USP2ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL97663 | 0.78 | GAA (0.65) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL3680719 | 0.78 | SLC6A2 (0.43) | ALDH1A1ESR1ESR2TP53TDP1 | |
| SCHEMBL27776962 | 0.77 | ALDH1A1 (0.44) | USP2ALDH1A1GAAPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1969028-A2 | POLYCARBONATES CONTAINING LOW LEVELS OF METHYL SALICYLATE PREPARED BY A MELT POLYMERIZATION IN A REACTIVE EXTRUDER | GENERAL ELECTRIC COMPANY (US) | 2008-09-17 | — | — | EP | disclosed |
| EP-1751211-B1 | METHOD FOR PREPARING A POLYCARBONATE OLIGOMER MIXTURE AT LOW TEMPERATURE FOR MANUFACTURING POLYCARBONATE | GEN ELECTRIC (US) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007075351-A2 | POLYCARBONATES CONTAINING LOW LEVELS OF METHYL SALICYLATE PREPARED BY A MELT POLYMERIZATION IN A REACTIVE EXTRUDER | GENERAL ELECTRIC COMPANY (US) | 2007-07-05 | — | — | WO | disclosed |