Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 12/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19583533 | 1.00 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL28841783 | 0.88 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL5445373 | 0.87 | TSHR (0.56) | PNMTADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL19584353 | 0.87 | PNMT (0.49) | PNMTADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL20957756 | 0.87 | PNMT (0.49) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL27961755 | 0.85 | PNMT (0.47) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL5448043 | 0.80 | TSHR (0.55) | PNMTADRA2AADRA2BADRA2C | |
| Butane SCHEMBL28279046 | 0.79 | PNMT (0.49) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL30762013 | 0.77 | PNMT (0.54) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL19583500 | 0.77 | PNMT (0.40) | PNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071525-B | Dimeric compounds | 豪夫迈·罗氏有限公司 | 2022-08-19 | — | — | CN | disclosed |