Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KAT7 | O95251 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25472502 | 1.00 | NAMPT (0.37) | NAMPTKAT6AKAT5GPR119EPHX2 | |
| SCHEMBL26610940 | 0.91 | NAMPT (0.38) | NAMPTKAT6AKAT5GPR119ALOX5AP | |
| SCHEMBL26610938 | 0.91 | NAMPT (0.38) | NAMPTKAT6AKAT5GPR119ALOX5AP | |
| SCHEMBL26610939 | 0.91 | NAMPT (0.38) | NAMPTKAT6AKAT5GPR119ALOX5AP | |
| SCHEMBL25094741 | 0.84 | NAMPT (0.39) | NAMPTKAT6AKAT5GPR119ALOX5AP | |
| SCHEMBL26728704 | 0.83 | NAMPT (0.38) | NAMPTKAT6AKAT5GPR119EPHX2 | |
| SCHEMBL26696289 | 0.83 | NAMPT (0.38) | NAMPTKAT6AKAT5GPR119EPHX2 | |
| SCHEMBL27138352 | 0.83 | NAMPT (0.38) | NAMPTKAT6AKAT5GPR119EPHX2 | |
| SCHEMBL23326529 | 0.78 | GPR119 (0.36) | GPR119SOS1USP30 | |
| SCHEMBL23326528 | 0.78 | GPR119 (0.36) | GPR119SOS1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187411-A1 | HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2022-09-09 | — | — | WO | disclosed |