Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL661687 | 0.83 | ERCC5 (0.43) | ALDH1A1ERCC5FEN1MAPTKMT2A | |
| SCHEMBL27871718 | 0.81 | ERCC5 (0.43) | ALDH1A1ERCC5FEN1MAPTKMT2A | |
| SCHEMBL7799733 | 0.81 | ALDH1A1 (0.42) | ALDH1A1ERCC5FEN1MAPTSMN1; SMN2 | |
| SCHEMBL660111 | 0.81 | RAB9A (0.46) | ALDH1A1ERCC5FEN1MAPTSMN1; SMN2 | |
| SCHEMBL660093 | 0.80 | ALDH1A1 (0.44) | ALDH1A1ERCC5FEN1MAPTSMN1; SMN2 | |
| SCHEMBL661571 | 0.79 | RAB9A (0.52) | ALDH1A1ERCC5FEN1MAPTKMT2A | |
| SCHEMBL286969 | 0.78 | ALDH1A1 (0.42) | ALDH1A1ERCC5FEN1SMN1; SMN2KMT2A | |
| SCHEMBL661019 | 0.78 | NPSR1 (0.43) | ALDH1A1ERCC5FEN1SMN1; SMN2KMT2A | |
| SCHEMBL287219 | 0.78 | TSHR (0.42) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL287773 | 0.78 | ALDH1A1 (0.39) | ALDH1A1ERCC5FEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |