Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12491518 | 1.00 | MDM4 (0.51) | MDM4TP53CASP3KDM4ASLC17A5 | |
| SCHEMBL29929404 | 1.00 | MDM4 (0.51) | MDM4TP53CASP3KDM4ASLC17A5 | |
| SCHEMBL799728 | 1.00 | MDM4 (0.51) | MDM4TP53CASP3KDM4ASLC17A5 | |
| SCHEMBL15874657 | 0.88 | MDM2 (0.53) | MDM4TP53CASP3SLC17A5MDM2 | |
| SCHEMBL8697104 | 0.85 | MDM4 (0.48) | MDM4TP53CASP3SLC17A5MDM2 | |
| SCHEMBL19678477 | 0.85 | MDM4 (0.59) | MDM4TP53CASP3SLC17A5MDM2 | |
| SCHEMBL2306646 | 0.83 | MDM4 (0.51) | MDM4TP53CASP3MDM2 | |
| SCHEMBL29400841 | 0.83 | MDM4 (0.51) | MDM4TP53CASP3MDM2 | |
| SCHEMBL800312 | 0.83 | MDM4 (0.51) | MDM4TP53CASP3MDM2 | |
| SCHEMBL29355438 | 0.83 | MDM4 (0.51) | MDM4TP53CASP3MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115142141-A | Cyclic compound library and method for constructing same | 亚飞（上海）生物医药科技有限公司 | 2022-10-04 | — | — | CN | disclosed |