Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29899340 | 1.00 | MDM4 (0.51) | MDM4TP53CASP3KDM4ASLC17A5 | |
| SCHEMBL12491518 | 1.00 | MDM4 (0.51) | MDM4TP53CASP3KDM4ASLC17A5 | |
| SCHEMBL29929404 | 1.00 | MDM4 (0.51) | MDM4TP53CASP3KDM4ASLC17A5 | |
| SCHEMBL15874657 | 0.88 | MDM2 (0.53) | MDM4TP53CASP3SLC17A5MDM2 | |
| SCHEMBL8697104 | 0.85 | MDM4 (0.48) | MDM4TP53CASP3SLC17A5MDM2 | |
| SCHEMBL19678477 | 0.85 | MDM4 (0.59) | MDM4TP53CASP3SLC17A5MDM2 | |
| SCHEMBL2306646 | 0.83 | MDM4 (0.51) | MDM4TP53CASP3MDM2 | |
| SCHEMBL29400841 | 0.83 | MDM4 (0.51) | MDM4TP53CASP3MDM2 | |
| SCHEMBL800312 | 0.83 | MDM4 (0.51) | MDM4TP53CASP3MDM2 | |
| SCHEMBL29355438 | 0.83 | MDM4 (0.51) | MDM4TP53CASP3MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | NEW YORK UNIVERSITY (US) | 2026-01-01 | — | — | US | disclosed |
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2025-07-29 | — | — | US | disclosed |
| EP-3303367-B1 | STABILIZED MINIMAL COILED-COIL MIMETICS | UNIV NEW YORK (US) | 2025-06-18 | — | — | EP | disclosed |
| US-20240190930-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | UNIV NEW YORK (US) | 2024-06-13 | — | — | US | disclosed |
| US-20240124539-A1 | CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME | NEW YORK UNIVERSITY | 2024-04-18 | — | — | US | disclosed |
| US-11891422-B2 | NEMO coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2024-02-06 | — | — | US | disclosed |
| US-20220289802-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | CORNELL UNIVERSITY | 2022-09-15 | — | — | US | disclosed |
| US-11440938-B2 | Stabilized minimal coiled-coil mimetics | NEW YORK UNIVERSITY (US) | 2022-09-13 | — | — | US | disclosed |
| US-20210277059-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | UNIV NEW YORK (US) | 2021-09-09 | — | — | US | disclosed |
| US-10851133-B2 | Stabilized minimal coiled-coil mimetics | NEW YORK UNIVERSITY (US) | 2020-12-01 | — | — | US | disclosed |
| US-20110136697-A1 | METHODS FOR SYNTHESIS OF ENCODED LIBRARIES | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2011-06-09 | — | — | US | disclosed |
| US-20110136697-A1 | METHODS FOR SYNTHESIS OF ENCODED LIBRARIES | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2011-06-09 | — | — | US | disclosed |
| US-7935658-B2 | Methods for synthesis of encoded libraries | PRAECIS PHARMACEUTICALS, INC. (US) | 2011-05-03 | — | — | US | disclosed |
| US-7935658-B2 | Methods for synthesis of encoded libraries | PRAECIS PHARMACEUTICALS, INC. (US) | 2011-05-03 | — | — | US | disclosed |
| US-20090062147-A1 | Methods for synthesis of encoded libraries | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2009-03-05 | — | — | US | disclosed |
| US-20090062147-A1 | Methods for synthesis of encoded libraries | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2009-03-05 | — | — | US | disclosed |
| US-20070224607-A1 | Methods for identifying compounds of interest using encoded libraries | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2007-09-27 | — | — | US | disclosed |
| US-20070224607-A1 | Methods for identifying compounds of interest using encoded libraries | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2007-09-27 | — | — | US | disclosed |
| US-20070042401-A1 | Methods for synthesis of encoded libraries | PRAECIS PHARMACEUTICALS, INC. (US) | 2007-02-22 | — | — | US | disclosed |
| US-20070042401-A1 | Methods for synthesis of encoded libraries | PRAECIS PHARMACEUTICALS, INC. (US) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | MDM4 2743/4885TP53 3446/4885CASP3 3773/4885 |
| US-11440938-B2 | Stabilized minimal coiled-coil mimetics | COIL, CALCOCO2, SMC2 | MDM4 256/4885TP53 657/4885CASP3 3879/4885 |
| US-10851133-B2 | Stabilized minimal coiled-coil mimetics | COIL, CALCOCO2, CRYZ | MDM4 296/4885TP53 679/4885CASP3 3941/4885 |
| US-20210277059-A1 | STABILIZED MINIMAL COILED-COIL MIMETICS | COIL, CALCOCO2, CRYZ | MDM4 296/4885TP53 679/4885CASP3 3941/4885 |
| US-20240124539-A1 | CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME | SOS2, SOS1, F2 | MDM4 2834/4885TP53 2795/4885CASP3 3344/4885 |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | DDX21, PHAX, RBX1 | MDM4 2407/4885TP53 2772/4885CASP3 3274/4885 |
| US-11891422-B2 | NEMO coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | MDM4 2743/4885TP53 3446/4885CASP3 3773/4885 |
| US-20220289802-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | COIL, CALCOCO2, NCAPH | MDM4 2743/4885TP53 3446/4885CASP3 3773/4885 |
| US-20240190930-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | COIL, CALCOCO2, NCAPH | MDM4 2503/4885TP53 3371/4885CASP3 3752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.