Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23092695 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTHPGDMAOA | |
| SCHEMBL20872955 | 0.81 | MAOA (0.54) | ALDH1A1KDM4EMAPTHPGDMAOA | |
| SCHEMBL4014797 | 0.80 | MAOA (0.59) | ALDH1A1KDM4EMAPTHPGDMAOA | |
| SCHEMBL1815790 | 0.79 | POLB (0.51) | ALDH1A1KDM4EMAPTHPGDMAOA | |
| SCHEMBL10263771 | 0.78 | POLB (0.69) | MAOAMAOBPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL11825101 | 0.78 | MAOB (0.50) | ALDH1A1KDM4EMAPTHPGDMAOA | |
| SCHEMBL1818633 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDMAOAMAOB | |
| SCHEMBL23092860 | 0.76 | POLB (0.55) | MAPTMAOAMAOBPOLBKMT2A | |
| SCHEMBL23092362 | 0.76 | POLB (0.55) | ALDH1A1MAOAMAOBPOLBCYP1A2 | |
| SCHEMBL8781008 | 0.76 | POLB (0.55) | ALDH1A1HPGDMAOAMAOBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115038688-A | USP30 inhibitors and uses thereof | 文森雷生物科学股份有限公司 | 2022-09-09 | — | — | CN | disclosed |