SCHEMBL2990097

SCHEMBL2990097

CCC1(C)CC(C(C)(C)C2CC(C)(CC)c3ccccc32)c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.35
CYP3A4 P08684 2/20 0.34
MEN1 O00255 1/20 0.34
CYP2D6 P10635 1/20 0.34
ALOX15 P16050 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
BCHE P06276 1/20 0.34
CHRM5 P08912 1/20 0.34
TSHR P16473 1/20 0.34
ALOX12 P18054 1/20 0.34
NFKB1 P19838 1/20 0.34
MAPK1 P28482 1/20 0.34
PRCP P42785 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2999466 0.94 HTR2C (0.33) HTR2ACYP3A4MEN1CYP2D6ALOX15
SCHEMBL2988144 0.93 HTR2A (0.31) HTR2ACYP3A4MEN1CYP2D6ALOX15
SCHEMBL10316488 0.81 HTR2A (0.35) HTR2ACYP3A4MEN1CYP2D6ALOX15
SCHEMBL2993915 0.79 CYP3A4 (0.38) HTR2ACYP3A4MEN1CYP2D6ALOX15
SCHEMBL2993024 0.73 HTR2A (0.35) HTR2ACYP3A4MEN1CYP2D6ALOX15
SCHEMBL2995990 0.69 HTR2C (0.36) HTR2AKDM1ARCOR1
SCHEMBL2994793 0.68 HTR2A (0.31) HTR2AKDM1ARCOR1
SCHEMBL27473432 0.63 BRD4 (0.40) HTR2AMEN1ALOX15KMT2AKDM1A
SCHEMBL15613866 0.63 TAAR1 (0.36) HTR2A
SCHEMBL23330386 0.61 SIGMAR1 (0.38) CYP3A4MEN1CYP2D6ALOX15CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed