Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.65 |
| ▸ | POLB | P06746 | 8/20 | 0.65 |
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | RECQL | P46063 | 6/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | EIF4E | P06730 | 1/20 | 0.65 |
| ▸ | EIF4G1 | Q04637 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.58 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.58 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29901228 | 0.87 | PTPN22 (0.62) | MEN1KMT2APOLBMAPTTDP1 | |
| SCHEMBL3904183 | 0.87 | PTPN12 (0.66) | MEN1KMT2APOLBMAPTTDP1 | |
| SCHEMBL3904180 | 0.87 | PTPN12 (0.66) | MEN1KMT2APOLBMAPTTDP1 | |
| SCHEMBL30477056 | 0.87 | MEN1 (0.68) | MEN1KMT2APOLBMAPTTDP1 | |
| SCHEMBL3896597 | 0.86 | LCK (0.68) | MEN1KMT2APOLBMAPTTDP1 | |
| SCHEMBL29554158 | 0.86 | LCK (0.68) | MEN1KMT2APOLBMAPTTDP1 | |
| SCHEMBL3896603 | 0.86 | LCK (0.68) | MEN1KMT2APOLBMAPTTDP1 | |
| SCHEMBL29493548 | 0.83 | KMT2A (0.67) | MEN1KMT2APOLBMAPTTDP1 | |
| SCHEMBL29901257 | 0.83 | KMT2A (0.77) | MEN1KMT2APOLBMAPTTDP1 | |
| SCHEMBL29883557 | 0.82 | PTPN22 (0.75) | MEN1KMT2APOLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4269437-A1 | PD-1 BINDING MOLECULE AND APPLICATION THEREOF | Zhejiang Nanomab Technology Center Co. Ltd. (CN) | 2023-11-01 | — | — | EP | disclosed |
| CN-116829718-A | PD-1 binding molecules and uses thereof | 浙江纳米抗体技术中心有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2022143552-A1 | PD-1 BINDING MOLECULE AND APPLICATION THEREOF | 浙江纳米抗体技术中心有限公司 | 2022-07-07 | — | — | WO | disclosed |