SCHEMBL29554158

SCHEMBL29554158

O=C(O)c1cccc(-c2ccc(/C=C3\SC(=S)N(c4cccc(F)c4)C3=O)o2)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.68
APEX1 P27695 1/20 0.66
DUSP22 Q9NRW4 5/20 0.61
MEN1 O00255 3/20 0.60
POLB P06746 3/20 0.60
KMT2A Q03164 3/20 0.60
ALDH1A1 P00352 2/20 0.60
L3MBTL1 Q9Y468 2/20 0.60
MAPT P10636 2/20 0.60
KDM4E B2RXH2 1/20 0.60
LMNA P02545 1/20 0.60
GAA P10253 1/20 0.60
MAPK1 P28482 1/20 0.60
RECQL P46063 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
SAE1 Q9UBE0 1/20 0.60
UBA2 Q9UBT2 1/20 0.60
GPR55 Q9Y2T6 1/20 0.60
MAP3K5 Q99683 1/20 0.59
PIK3CG P48736 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3896603 1.00 LCK (0.68) LCKAPEX1DUSP22MEN1POLB
SCHEMBL3896597 1.00 LCK (0.68) LCKAPEX1DUSP22MEN1POLB
SCHEMBL3904180 0.92 PTPN12 (0.66) LCKAPEX1DUSP22MEN1POLB
SCHEMBL29908306 0.92 LCK (0.80) LCKAPEX1DUSP22MEN1POLB
SCHEMBL3904183 0.92 PTPN12 (0.66) LCKAPEX1DUSP22MEN1POLB
SCHEMBL3892654 0.92 APEX1 (0.71) LCKAPEX1DUSP22MEN1POLB
SCHEMBL3892650 0.92 APEX1 (0.71) LCKAPEX1DUSP22MEN1POLB
SCHEMBL3896309 0.90 MEN1 (0.68) LCKAPEX1DUSP22MEN1POLB
SCHEMBL3896302 0.90 MEN1 (0.68) LCKAPEX1DUSP22MEN1POLB
SCHEMBL29554356 0.90 MEN1 (0.68) LCKAPEX1DUSP22MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112500482-B Gold glucose specific nano antibody and double-antibody sandwich ELISA (enzyme-Linked immuno sorbent assay) method thereof 南开大学(CN) 2023-01-13 CN claimed
US-20250312367-A1 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF ADARX PHARMACEUTICALS, INC. (US) 2025-10-09 US disclosed
CN-119798441-A Anti-TRAIL nano antibody and application thereof 河南大学 2025-04-11 CN disclosed
EP-4522628-A2 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF Adarx Pharmaceuticals, Inc. (US) 2025-03-19 EP disclosed
US-20240124575-A1 HUMAN CD33 ANTIBODY AND USE THEREOF HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO., LTD. (CN) 2024-04-18 US disclosed
US-20240076403-A1 HER2 ANTIBODY AND APPLICATION THEREOF HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO. LTD. (CN) 2024-03-07 US disclosed
WO-2023220737-A2 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF ADARX PHARMACEUTICALS, INC. (US) 2023-11-16 WO disclosed
EP-4269437-A1 PD-1 BINDING MOLECULE AND APPLICATION THEREOF Zhejiang Nanomab Technology Center Co. Ltd. (CN) 2023-11-01 EP disclosed
CN-116867806-A Human CD33 antibodies and uses thereof 先声再明医药有限公司 2023-10-10 CN disclosed
CN-116829718-A PD-1 binding molecules and uses thereof 浙江纳米抗体技术中心有限公司 2023-09-29 CN disclosed
US-20230097398-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS ELOXX PHARMACEUTICALS LTD. (IL) 2023-03-30 US disclosed
US-11613551-B2 Aminoglycoside derivatives and uses thereof in treating genetic disorders ELOXX PHARMACEUTICALS LTD. (IL) 2023-03-28 US disclosed
CN-112500482-B Gold glucose specific nano antibody and double-antibody sandwich ELISA (enzyme-Linked immuno sorbent assay) method thereof 南开大学(CN) 2023-01-13 CN disclosed
CN-112500482-B Gold glucose specific nano antibody and double-antibody sandwich ELISA (enzyme-Linked immuno sorbent assay) method thereof 南开大学(CN) 2023-01-13 CN disclosed
CN-114957357-A Aminoglycoside derivatives and their use in the treatment of genetic disorders ELOXX制药有限公司 2022-08-30 CN disclosed
WO-2022171113-A1 HUMAN CD33 ANTIBODY AND USE THEREOF 江苏先声药业有限公司 2022-08-18 WO disclosed
WO-2022143552-A1 PD-1 BINDING MOLECULE AND APPLICATION THEREOF 浙江纳米抗体技术中心有限公司 2022-07-07 WO disclosed
WO-2022127889-A1 HER2 ANTIBODY AND APPLICATION THEREOF 江苏先声药业有限公司 2022-06-23 WO disclosed
CN-108350014-B Aminoglycoside derivatives and their use in the treatment of genetic disorders ELOXX制药有限公司 2022-06-10 CN disclosed
US-11306115-B2 Aminoglycoside derivatives and uses thereof in treating genetic disorders ELOXX PHARMACEUTICALS LTD. (IL) 2022-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230097398-A1 AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS UPF1, IDUA, UGGT1 LCK 4777/4885APEX1 3273/4885DUSP22 2210/4885
US-11306115-B2 Aminoglycoside derivatives and uses thereof in treating genetic disorders UPF1, IDUA, UGGT1 LCK 4777/4885APEX1 3273/4885DUSP22 2210/4885
US-20250312367-A1 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF POLRMT, TARDBP, NSUN2 LCK 1390/4885APEX1 1098/4885DUSP22 4220/4885
US-11613551-B2 Aminoglycoside derivatives and uses thereof in treating genetic disorders UPF1, AARS1, NUDT21 LCK 4774/4885APEX1 2597/4885DUSP22 3930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.