Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22274905 | 1.00 | PDE9A (0.38) | PDE9AALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL24203389 | 0.86 | ALDH1A1 (0.38) | PDE9AALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL21840082 | 0.74 | KMT2A (0.36) | PDE9AALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL29901239 | 0.74 | PDE9A (0.50) | PDE9A | |
| SCHEMBL22274912 | 0.73 | PDE9A (0.37) | PDE9AALDH1A1L3MBTL1MAPK1HTT | |
| SCHEMBL20870600 | 0.73 | RECQL (0.38) | PDE9AALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL29901256 | 0.72 | PDE9A (0.62) | PDE9A | |
| SCHEMBL22274904 | 0.72 | PDE9A (0.62) | PDE9A | |
| SCHEMBL22274911 | 0.71 | HTT (0.31) | L3MBTL1HTT | |
| SCHEMBL29901261 | 0.71 | HTT (0.31) | L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471059-B | PDE9 inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-111658653-B | Use of phosphodiesterase inhibitors | 药捷安康(南京)科技股份有限公司 | 2022-09-09 | — | — | CN | disclosed |