SCHEMBL29901566

SCHEMBL29901566

C[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCC(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 1/20 0.48
▸ FAP Q12884 1/20 0.48
▸ DPP8 Q6V1X1 1/20 0.48
▸ DPP9 Q86TI2 1/20 0.48
▸ DPP7 Q9UHL4 1/20 0.48
▸ ACE P12821 2/20 0.48
▸ REN P00797 1/20 0.48
▸ XIAP P98170 1/20 0.45
▸ GRB2 P62993 1/20 0.44
▸ OPRM1 P35372 2/20 0.42
▸ OPRD1 P41143 1/20 0.42
▸ OPRK1 P41145 1/20 0.42
▸ SLC6A2 P23975 1/20 0.41
▸ F2 P00734 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29641766 0.91 ACE (0.54) DPP4FAPDPP8DPP9DPP7
SCHEMBL30844353 0.91 CALCRL (0.46) DPP4FAPDPP8DPP9DPP7
SCHEMBL30844271 0.89 CALCRL (0.48) XIAPGRB2F2
SCHEMBL29641611 0.88 DPP4 (0.55) DPP4FAPDPP8DPP9DPP7
SCHEMBL30585207 0.87 CALCRL (0.46) SLC6A2
SCHEMBL29630700 0.87 GRB2 (0.44) XIAPGRB2OPRM1OPRD1OPRK1
SCHEMBL31126288 0.87 OPRM1 (0.42) ACERENOPRM1OPRD1F2
SCHEMBL30974114 0.86 CAPN1 (0.46) XIAPGRB2OPRM1OPRD1OPRK1
SCHEMBL31696320 0.85 CTSD (0.45) DPP4FAPDPP8DPP9DPP7
SCHEMBL29470192 0.85 ACE (0.50) DPP4FAPDPP8DPP9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4654997-A1 SARS-COV-2 VACCINE CONSTRUCTS Rutgers, The State University of New Jersey (US) 2025-12-03 — — EP claimed
US-20250345415-A1 SARS-CoV-2 Vaccine Constructs RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2025-11-13 — — US claimed
WO-2024158722-A1 SARS-COV-2 VACCINE CONSTRUCTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-08-02 — — WO claimed
EP-4654997-A1 SARS-COV-2 VACCINE CONSTRUCTS Rutgers, The State University of New Jersey (US) 2025-12-03 — — EP disclosed
US-20250345415-A1 SARS-CoV-2 Vaccine Constructs RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2025-11-13 — — US disclosed
US-20250304664-A1 Human NTCP Binders For Therapeutic Use And Liver-Specific Targeted Delivery VIB VZW (BE) 2025-10-02 — — US disclosed
US-20250230197-A1 MALARIA VACCINE UNIV OXFORD INNOVATION LTD (GB) 2025-07-17 — — US disclosed
EP-4463479-A1 HUMAN NTCP BINDERS FOR THERAPEUTIC USE AND LIVER-SPECIFIC TARGETED DELIVERY VIB VZW (BE) 2024-11-20 — — EP disclosed
WO-2024158722-A1 SARS-COV-2 VACCINE CONSTRUCTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-08-02 — — WO disclosed
WO-2023135198-A1 HUMAN NTCP BINDERS FOR THERAPEUTIC USE AND LIVER-SPECIFIC TARGETED DELIVERY VIB VZW (BE) 2023-07-20 — — WO disclosed
US-20220411495-A1 POSITIVE ALLOSTERIC MODULATORS OF THE CALCIUM-SENSING RECEPTOR UNIVERSITY OF COPENHAGEN (DK) 2022-12-29 — — US disclosed
EP-4065603-A1 POSITIVE ALLOSTERIC MODULATORS OF THE CALCIUM-SENSING RECEPTOR VIB VZW (BE) 2022-10-05 — — EP disclosed
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