Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16541627 | 0.89 | PGR (0.34) | ALDH1A1PGR | |
| SCHEMBL30704859 | 0.87 | PGR (0.32) | ALDH1A1PGR | |
| SCHEMBL900663 | 0.87 | PGR (0.32) | ALDH1A1PGR | |
| SCHEMBL28062084 | 0.85 | PGR (0.31) | ALDH1A1PGR | |
| SCHEMBL20692934 | 0.84 | NR3C2 (0.34) | ALDH1A1NR3C2PGRREN | |
| SCHEMBL25362198 | 0.82 | ALDH1A1 (0.37) | ALDH1A1MAPTRECQLNR3C2KMT2A | |
| SCHEMBL30799184 | 0.82 | NR3C2 (0.36) | ALDH1A1NR3C2REN | |
| SCHEMBL20693048 | 0.82 | NR3C2 (0.36) | ALDH1A1NR3C2REN | |
| SCHEMBL30193857 | 0.82 | ALDH1A1 (0.37) | ALDH1A1MAPTRECQLNR3C2KMT2A | |
| SCHEMBL26001531 | 0.79 | ALDH1A1 (0.37) | ALDH1A1MAPTRECQLNR3C2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200985-B | Pteridinone compound and preparation method and application thereof | 南开大学 | 2022-09-09 | — | — | CN | disclosed |