Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14498908 | 1.00 | NFKB1 (0.32) | NFKB1NFKB2RELATNKSTNKS2 | |
| SCHEMBL8535407 | 0.71 | — | — | |
| SCHEMBL613700 | 0.71 | — | — | |
| SCHEMBL8532549 | 0.71 | — | — | |
| SCHEMBL28860808 | 0.69 | — | — | |
| SCHEMBL13241618 | 0.68 | SIRT2 (0.34) | — | |
| SCHEMBL3001617 | 0.68 | SIRT2 (0.34) | — | |
| SCHEMBL15195736 | 0.68 | SIRT2 (0.34) | — | |
| SCHEMBL8531191 | 0.67 | TNKS (0.33) | TNKSTNKS2 | |
| SCHEMBL15496326 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513442-B2 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions | THE UNIVERSITY OF CHICAGO (US) | 2013-08-20 | — | — | US | disclosed |
| US-8513442-B2 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions | THE UNIVERSITY OF CHICAGO (US) | 2013-08-20 | — | — | US | disclosed |
| US-8513442-B2 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions | THE UNIVERSITY OF CHICAGO (US) | 2013-08-20 | — | — | US | disclosed |
| US-20100184999-A1 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions | THE UNIVERSITY OF CHICAGO | 2010-07-22 | — | — | US | disclosed |
| US-20100184999-A1 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions | THE UNIVERSITY OF CHICAGO | 2010-07-22 | — | — | US | disclosed |
| US-20100184999-A1 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions | THE UNIVERSITY OF CHICAGO | 2010-07-22 | — | — | US | disclosed |
| US-20080227851-A1 | LAULIMALIDE AND LAULIMALIDE ANALOGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-18 | — | — | US | disclosed |
| US-20080227851-A1 | LAULIMALIDE AND LAULIMALIDE ANALOGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-18 | — | — | US | disclosed |
| US-7230125-B1 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions | THE UNIVERSITY OF CHICAGO (US) | 2007-06-12 | — | — | US | disclosed |
| US-7230125-B1 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions | THE UNIVERSITY OF CHICAGO (US) | 2007-06-12 | — | — | US | disclosed |
| US-7230125-B1 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions | THE UNIVERSITY OF CHICAGO (US) | 2007-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227851-A1 | LAULIMALIDE AND LAULIMALIDE ANALOGS | SSB, LPXN, LTA | NFKB1 1933/4885NFKB2 2195/4885RELA 4118/4885 |
| US-20100184999-A1 | Methods of performing cycloadditions, reaction mixtures, and methods of performing asymmetric catalytic reactions | DCXR, POR, COASY | NFKB1 3228/4885NFKB2 3789/4885RELA 4071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.